[HTML][HTML] Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach
Editorial summary Personalized care of cancer patients undergoing treatment with immune
checkpoint inhibitors will require approaches that can predict their susceptibility to immune-
related adverse events. Understanding the role of germline genetic factors in determining
individual responses to immunotherapy will deepen our understanding of immune toxicity
and, importantly, it may lead to tools for identifying patients who are at risk.
checkpoint inhibitors will require approaches that can predict their susceptibility to immune-
related adverse events. Understanding the role of germline genetic factors in determining
individual responses to immunotherapy will deepen our understanding of immune toxicity
and, importantly, it may lead to tools for identifying patients who are at risk.
Editorial summary
Personalized care of cancer patients undergoing treatment with immune checkpoint inhibitors will require approaches that can predict their susceptibility to immune-related adverse events. Understanding the role of germline genetic factors in determining individual responses to immunotherapy will deepen our understanding of immune toxicity and, importantly, it may lead to tools for identifying patients who are at risk.
Springer