Food restriction selectively increases hypothalamic orexin-B levels in lactating rats
XJ Cai, R Denis, RG Vernon, JC Clapham, S Wilson… - Regulatory peptides, 2001 - Elsevier
Orexins are hypothalamic peptides implicated in the regulation of ingestive and other
behaviours. Here we investigated prepro-orexin expression and hypothalamic orexin-A and-
B levels in lactating rats, which display marked hyperphagia, with or without food restriction
for 2 days or treatment with bromocriptine, which inhibits milk production and thus reduces
the energy losses of lactation. Neither prepro-orexin gene expression nor hypothalamic
orexin-A peptide levels were changed in any of these lactating groups compared with age …
behaviours. Here we investigated prepro-orexin expression and hypothalamic orexin-A and-
B levels in lactating rats, which display marked hyperphagia, with or without food restriction
for 2 days or treatment with bromocriptine, which inhibits milk production and thus reduces
the energy losses of lactation. Neither prepro-orexin gene expression nor hypothalamic
orexin-A peptide levels were changed in any of these lactating groups compared with age …
