[HTML][HTML] C5b-9 staining correlates with clinical and tumor stage in gastric adenocarcinoma
J Chen, W Yang, H Sun, X Yang… - … & Molecular Morphology, 2016 - journals.lww.com
The complement system is a critical part of the immune response, acting in defense against
viral infections, clearance of immune complexes, and maintenance of tissue homeostasis.
Upregulated expression of the terminal complement complex, C5b-9, has been observed on
various tumor cells, such as stomach carcinoma cells, and on cells in the necrotic regions of
these tumors as well; however, whether and how C5b-9 is related to gastric cancer
progression and severity remains unknown. In this study, human gastric adenocarcinoma …
viral infections, clearance of immune complexes, and maintenance of tissue homeostasis.
Upregulated expression of the terminal complement complex, C5b-9, has been observed on
various tumor cells, such as stomach carcinoma cells, and on cells in the necrotic regions of
these tumors as well; however, whether and how C5b-9 is related to gastric cancer
progression and severity remains unknown. In this study, human gastric adenocarcinoma …