Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver …

R Klein, CE Myers, KJ Cruickshanks… - JAMA …, 2014 - jamanetwork.com
Importance Modifying levels of factors associated with age-related macular degeneration
(AMD) may decrease the risk for visual impairment in older persons. Objective To examine
the relationships of markers of inflammation, oxidative stress, and endothelial dysfunction to
the 20-year cumulative incidence of early AMD. Design, Setting, and Participants This
longitudinal population-based cohort study involved a random sample of 975 persons in the
Beaver Dam Eye Study without signs of AMD who participated in the baseline examination …