Objectives Current methods for the early detection of prostate cancer (PCa), in particular
prostate-specific antigen screening, are likely to benefit from complementary molecular
analyses to enhance specificity. MicroRNAs (miRNA) are small endogenously expressed
noncoding RNAs that negatively regulate the expression of protein-coding genes at the
transcriptional or translational level. Accumulating evidence suggests that miRNAs play an
important role in tumorigenesis, are differentially expressed in different cancer types, and …