Low-dose aspirin does not increase implantation rates in patients undergoing intracytoplasmic sperm injection: a prospective randomized study
B Urman, R Mercan, C Alatas, B Balaban… - Journal of assisted …, 2000 - Springer
B Urman, R Mercan, C Alatas, B Balaban, A Isiklar, A Nuhoglu
Journal of assisted reproduction and genetics, 2000•SpringerPurpose: The aim was to evaluate the effect of aspirin on pregnancy and implantation rates
in an unselected group of patients undergoing intracytoplasmic sperm injection (ICSI).
Methods: Two hundred and seventy-nine patients were randomized to receive 80 mg of
aspirin (n= 139) or no treatment (r= 136) starting from the first day of controlled ovarian
hyperstimulation. Results: Duration of stimulation, gonadotropin consumption, peak
estradiol, number of oocytes retrieved, fertilization rate, cleavage rate, and number of …
in an unselected group of patients undergoing intracytoplasmic sperm injection (ICSI).
Methods: Two hundred and seventy-nine patients were randomized to receive 80 mg of
aspirin (n= 139) or no treatment (r= 136) starting from the first day of controlled ovarian
hyperstimulation. Results: Duration of stimulation, gonadotropin consumption, peak
estradiol, number of oocytes retrieved, fertilization rate, cleavage rate, and number of …
Abstract
Purpose: The aim was to evaluate the effect of aspirin on pregnancy and implantation rates in an unselected group of patients undergoing intracytoplasmic sperm injection (ICSI).
Methods: Two hundred and seventy-nine patients were randomized to receive 80 mg of aspirin (n = 139) or no treatment (r = 136) starting from the first day of controlled ovarian hyperstimulation.
Results: Duration of stimulation, gonadotropin consumption, peak estradiol, number of oocytes retrieved, fertilization rate, cleavage rate, and number of embryos transferred were similar in the two groups. Implantation and clinical pregnancy rates were 15.6% and 39.6% versus 15.1% and 43.4% in aspirin treated and untreated groups, respectively (P > 0.05).
Conclusions: Low-dose aspirin administration does not improve implantation and pregnancy rates in an unselected group of patients undergoing ICSI.
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