Maternal and infant factors predicting disease progression in human immunodeficiency virus type 1-infected infants

KC Rich, MG Fowler, LM Mofenson, R Abboud… - …, 2000 - publications.aap.org
Background. Infants with perinatally acquired human immunodeficiency virus type 1 (HIV-1)
infection have widely variable courses. Previous studies showed that a number of maternal
and infant factors, when analyzed separately, are associated with infant HIV-1 disease
progression. In this study, clincal, virologic, and immunologic characteristics in the mothers
and infants were examined together to determine the predictors of disease progression by
18 months of age and the associations with rapid progression during the first 6 months of …