Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004
O O'Toole, BJ Traynor, P Brennan… - Journal of Neurology …, 2008 - jnnp.bmj.com
Journal of Neurology, Neurosurgery & Psychiatry, 2008•jnnp.bmj.com
Background: We conducted a prospective, population based study to examine trends in
incidence and prevalence of amyotrophic lateral sclerosis (ALS) in Ireland from 1995 to
2004. Methods: The Irish ALS Register was used to identify Irish residents diagnosed with
ALS between the 3 year period from 1 January 1995 to 31 December 1997 and the 3 year
period from 1 January 2002 to 31 December 2004. Results: 465 Irish residents were
diagnosed with ALS during the study periods. The annual incidence rate of ALS in Ireland …
incidence and prevalence of amyotrophic lateral sclerosis (ALS) in Ireland from 1995 to
2004. Methods: The Irish ALS Register was used to identify Irish residents diagnosed with
ALS between the 3 year period from 1 January 1995 to 31 December 1997 and the 3 year
period from 1 January 2002 to 31 December 2004. Results: 465 Irish residents were
diagnosed with ALS during the study periods. The annual incidence rate of ALS in Ireland …
Background
We conducted a prospective, population based study to examine trends in incidence and prevalence of amyotrophic lateral sclerosis (ALS) in Ireland from 1995 to 2004.
Methods
The Irish ALS Register was used to identify Irish residents diagnosed with ALS between the 3 year period from 1 January 1995 to 31 December 1997 and the 3 year period from 1 January 2002 to 31 December 2004.
Results
465 Irish residents were diagnosed with ALS during the study periods. The annual incidence rate of ALS in Ireland remained stable over this time (2.0 cases per 100 000 person-years; 95% CI 1.9, 2.2). Median survival of Irish ALS patients was 16.4 months and did not change during the study period. Demographics and clinical features of the incident and prevalent Irish ALS cohorts were markedly different.
jnnp.bmj.com