Differential expression of Toll-like receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma
TJ Smith, K Yamamoto, M Kurata, A Yukimori… - … and molecular pathology, 2010 - Elsevier
Although Toll-like receptors (TLRs) in mammals are well-known to play important roles in
innate immunity, newer roles for the TLRs have suggested that cells with aberrant TLR
expression may have a survival advantage over normal cells. Lymphocytes are one of a
small number of cell types that express many of the TLRs, suggesting that abnormal TLR
levels/signaling may potentially influence the progression of malignant lymphomas. Thus,
frozen samples of 51 lymph nodes from patients with follicular lymphoma (FL), diffuse large …
innate immunity, newer roles for the TLRs have suggested that cells with aberrant TLR
expression may have a survival advantage over normal cells. Lymphocytes are one of a
small number of cell types that express many of the TLRs, suggesting that abnormal TLR
levels/signaling may potentially influence the progression of malignant lymphomas. Thus,
frozen samples of 51 lymph nodes from patients with follicular lymphoma (FL), diffuse large …