[PDF][PDF] Modulation of leptin resistance by protein tyrosine phosphatases
J St-Pierre, ML Tremblay - Cell metabolism, 2012 - cell.com
J St-Pierre, ML Tremblay
Cell metabolism, 2012•cell.comLeptin plays a central role in weight control by suppressing food intake and increasing
energy expenditure. The concept of leptin resistance emerged to explain the seemingly
paradoxical elevated leptin levels in obesity. Recent discoveries reveal that protein tyrosine
phosphatases are key players in leptin resistance by globally suppressing leptin signaling.
energy expenditure. The concept of leptin resistance emerged to explain the seemingly
paradoxical elevated leptin levels in obesity. Recent discoveries reveal that protein tyrosine
phosphatases are key players in leptin resistance by globally suppressing leptin signaling.
Leptin plays a central role in weight control by suppressing food intake and increasing energy expenditure. The concept of leptin resistance emerged to explain the seemingly paradoxical elevated leptin levels in obesity. Recent discoveries reveal that protein tyrosine phosphatases are key players in leptin resistance by globally suppressing leptin signaling.
cell.com
