Decrease of prefrontal metabolism after subthalamic stimulation in obsessive-compulsive disorder: a positron emission tomography study
BACKGROUND:: High-frequency bilateral subthalamic nucleus (STN) deep brain
stimulation (DBS) is a promising treatment in refractory obsessive-compulsive disorder
(OCD). METHOD:: Using the crossover, randomized, and double-blind procedure adopted
by the STOC study, 10 patients treated with high-frequency bilateral STN DBS underwent
am 18-fluorodeoxyglucose positron emission tomography (PET) investigation to highlight
the neural substratum of this therapeutic approach. RESULTS:: The median Yale–Brown …
stimulation (DBS) is a promising treatment in refractory obsessive-compulsive disorder
(OCD). METHOD:: Using the crossover, randomized, and double-blind procedure adopted
by the STOC study, 10 patients treated with high-frequency bilateral STN DBS underwent
am 18-fluorodeoxyglucose positron emission tomography (PET) investigation to highlight
the neural substratum of this therapeutic approach. RESULTS:: The median Yale–Brown …
