Smooth muscle cell proliferation in response to co-culture with venous and arterial endothelial cells
PN Waybill, VM Chinchilli, BJ Ballermann - Journal of vascular and …, 1997 - Elsevier
PURPOSE: The critical role of endothelial cells (ECs) in arterial disease is well established,
but little is known of their role in venous disease. Previous studies suggest inherent
differences between arteries and veins: arterial stenoses demonstrate a large lipid
component, whereas hemodialysis-related venous stenoses are characterized by marked
smooth muscle cell (SMC) proliferation. This study compares effects of venous versus
arterial ECs on SMC proliferation in co-culture. MATERIALS AND METHODS: Human …
but little is known of their role in venous disease. Previous studies suggest inherent
differences between arteries and veins: arterial stenoses demonstrate a large lipid
component, whereas hemodialysis-related venous stenoses are characterized by marked
smooth muscle cell (SMC) proliferation. This study compares effects of venous versus
arterial ECs on SMC proliferation in co-culture. MATERIALS AND METHODS: Human …
