Objective To conduct a therapeutic exploratory clinical trial comparing clinical outcomes of
treatment with topical natamycin vs topical voriconazole for fungal keratitis. Methods The
multicenter, double-masked, clinical trial included 120 patients with fungal keratitis at
Aravind Eye Hospital in India who were randomized to receive either topical natamycin or
topical voriconazole and either had repeated scraping of the epithelium or not. Main
Outcome Measures The primary outcome was best spectacle-corrected visual acuity …