[PDF][PDF] Aberrant protein interactions in amyloid disease
RM Vabulas, FU Hartl - Cell Cycle, 2011 - Taylor & Francis
RM Vabulas, FU Hartl
Cell Cycle, 2011•Taylor & FrancisAberrant protein interactions in amyloid disease Page 1 Cell Cycle 10:10, 1512-1513; May 15,
2011; © 2011 Landes Bioscience CeLL CyCLe Feature 1512 Cell Cycle Volume 10 Issue 10
The cellular protein network is highly complex and dynamic; thousands of new polypeptides are
constantly being synthesized on ribosomes, folded by molecular chaperones and transported
to their final destination. At the same time, obsolete and damaged proteins must be removed
by cytosolic or lysosomal protein degradation machineries. It is increasingly recognized that …
2011; © 2011 Landes Bioscience CeLL CyCLe Feature 1512 Cell Cycle Volume 10 Issue 10
The cellular protein network is highly complex and dynamic; thousands of new polypeptides are
constantly being synthesized on ribosomes, folded by molecular chaperones and transported
to their final destination. At the same time, obsolete and damaged proteins must be removed
by cytosolic or lysosomal protein degradation machineries. It is increasingly recognized that …
Comment on: Olzscha H, et al. Cell 2011; 144:67-78.
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