Genomic alterations of chromosome region 11p as predictive marker by array comparative genomic hybridization in lung adenocarcinoma patients

JS Sung, KH Park, YH Kim - Cancer Genetics and Cytogenetics, 2010 - Elsevier
Array comparative genomic hybridization (aCGH) provides a method to quantitatively
measure the changes of DNA copy number with an extremely high resolution and to map
them directly onto the complete linear genome sequences. In this study, we used aCGH to
compare genomic alterations in fresh-frozen lung cancer tissues of 21 adenocarcinomas
(AdCCs)(11 early relapse and 10 nonrelapse) and identified genomic alterations that
showed significant by different frequency between early relapse and nonrelapse AdCCs …