Differential diagnosis of periodic paralysis aided by in vitro myography
PA Iaizzo, S Quasthoff, F Lehmann-Horn - Neuromuscular Disorders, 1995 - Elsevier
In vitro twitch tests were performed on excised muscle bundles from 30 periodic paralysis
(PP) patients in an attempt to verify the somatic origin of PP, and to differentiate between the
hypokalemic (HypoPP) and the hyperkalemic forms (HyperPP). Seventeen PP patients with
a definite diagnosis of familial HypoPP, familial HyperPP (subsequently confirmed by
SCN4A mutations), or thyrotoxic PP entered the study, as well as 13 patients with a history of
attacks of weakness but with negative clinical provocation tests and therefore ambiguous …
(PP) patients in an attempt to verify the somatic origin of PP, and to differentiate between the
hypokalemic (HypoPP) and the hyperkalemic forms (HyperPP). Seventeen PP patients with
a definite diagnosis of familial HypoPP, familial HyperPP (subsequently confirmed by
SCN4A mutations), or thyrotoxic PP entered the study, as well as 13 patients with a history of
attacks of weakness but with negative clinical provocation tests and therefore ambiguous …
