[PDF][PDF] Randomized trial of hyperthermia and radiation for superficial tumors

EL Jones, JR Oleson, LR Prosnitz… - Journal of clinical …, 2005 - portmoodyhealth.com
EL Jones, JR Oleson, LR Prosnitz, TV Samulski, Z Vujaskovic, D Yu, LL Sanders…
Journal of clinical oncology, 2005portmoodyhealth.com
Purpose Randomized clinical trials have demonstrated hyperthermia (HT) enhances
radiation response. These trials, however, generally lacked rigorous thermal dose
prescription and administration. We report the final results of a prospective randomized trial
of superficial tumors (3 cm depth) comparing radiotherapy versus HT combined with
radiotherapy, using the parameter describing the number of cumulative equivalent minutes
at 43 C exceeded by 90% of monitored points within the tumor (CEM 43 CT 90) as a …
Purpose
Randomized clinical trials have demonstrated hyperthermia (HT) enhances radiation response. These trials, however, generally lacked rigorous thermal dose prescription and administration. We report the final results of a prospective randomized trial of superficial tumors (3 cm depth) comparing radiotherapy versus HT combined with radiotherapy, using the parameter describing the number of cumulative equivalent minutes at 43 C exceeded by 90% of monitored points within the tumor (CEM 43 CT 90) as a measure of thermal dose.
portmoodyhealth.com