[PDF][PDF] Calcium signaling: double duty for calcium at the mitochondrial uniporter

JW Putney, AP Thomas - Current biology, 2006 - cell.com
JW Putney, AP Thomas
Current biology, 2006cell.com
Uptake of Ca 2+ by mitochondria serves as a regulator of a number of important cellular
functions, including energy metabolism, cytoplasmic Ca 2+ signals, and apoptosis. Recent
findings reveal that the process of Ca 2+ uptake by the mitochondrial uniporter is itself
regulated by Ca 2+ in a temporally complex manner.
Uptake of Ca2+ by mitochondria serves as a regulator of a number of important cellular functions, including energy metabolism, cytoplasmic Ca2+ signals, and apoptosis. Recent findings reveal that the process of Ca2+ uptake by the mitochondrial uniporter is itself regulated by Ca2+ in a temporally complex manner.
cell.com