[HTML][HTML] Sterol carrier protein-2 expression modulates protein and lipid composition of lipid droplets

BP Atshaves, SM Storey, AL McIntosh… - Journal of Biological …, 2001 - ASBMB
Despite the critical role lipid droplets play in maintaining energy reserves and lipid stores for
the cell, little is known about the regulation of the lipid or protein components within the lipid
droplet. Although immunofluorescence of intact cells as well as Western analysis of isolated
lipid droplets revealed that sterol carrier protein-2 (SCP-2) was not associated with lipid
droplets, SCP-2 expression significantly altered the structure of the lipid droplet. First, the
targeting of fatty acid and cholesterol to the lipid droplets was significantly decreased …