The relationship of allergen-specific IgE levels and oral food challenge outcome

TT Perry, EC Matsui, MK Conover-Walker… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Oral food challenges remain the gold standard for the diagnosis of food
allergy. However, clear clinical and laboratory guidelines have not been firmly established to
determine when oral challenges should be performed. OBJECTIVE: We sought to determine
the value of food-specific IgE levels in predicting challenge outcome. METHODS: A
retrospective chart review of 604 food challenges in 391 children was performed. All
children had food-specific IgE levels measured by means of CAP-RAST before challenge …