[HTML][HTML] Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and …
KM Fournier, MI González, MB Robinson - Journal of Biological Chemistry, 2004 - ASBMB
The neuronal glutamate transporter, EAAC1, appears to both limit spillover between
excitatory synapses and provide precursor for the synthesis of the inhibitory
neurotransmitter, γ-aminobutyric acid. There is evidence for a large intracellular pool of
EAAC1 from which transporter is redistributed to the cell surface following activation of
protein kinase C (PKC) or platelet-derived growth factor (PDGF) receptor by seemingly
independent pathways. A variety of biotinylation strategies were employed to measure …
excitatory synapses and provide precursor for the synthesis of the inhibitory
neurotransmitter, γ-aminobutyric acid. There is evidence for a large intracellular pool of
EAAC1 from which transporter is redistributed to the cell surface following activation of
protein kinase C (PKC) or platelet-derived growth factor (PDGF) receptor by seemingly
independent pathways. A variety of biotinylation strategies were employed to measure …