Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics–induced obsessive-compulsive symptoms
JS Kwon, YH Joo, HJ Nam, M Lim… - Archives of general …, 2009 - jamanetwork.com
Context Several studies have indicated that atypical antipsychotics (AAP) induce obsessive-
compulsive (OC) symptoms. Research exploring the mechanism of this phenomenon,
however, has been extremely limited. Considering the indirect evidence of genetic control
and difficulties in developing animal models and performing gene expression studies,
genetic association studies could be an important approach to understanding the molecular
mechanism of AAP-induced OC symptoms. The glutamate transporter geneSLC1A1, which …
compulsive (OC) symptoms. Research exploring the mechanism of this phenomenon,
however, has been extremely limited. Considering the indirect evidence of genetic control
and difficulties in developing animal models and performing gene expression studies,
genetic association studies could be an important approach to understanding the molecular
mechanism of AAP-induced OC symptoms. The glutamate transporter geneSLC1A1, which …