[PDF][PDF] Survivin as a universal tumor antigen for novel cancer immunotherapy: functions of a killer clone

NA Aqui, RH Vonderheide - Cancer biology & therapy, 2008 - Taylor & Francis
NA Aqui, RH Vonderheide
Cancer biology & therapy, 2008Taylor & Francis
Survivin as a universal tumor antigen for novel cancer immunotherapy: Functions of a killer
clone Page 1 1888 Cancer Biology & Therapy 2008; Vol. 7 Issue 12 [Cancer Biology & Therapy
7:12, 1888-1889; December 2008]; ©2008 Landes Bioscience Survivin is expressed in virtually
every human cancer, whereas its expression in normal tissue is low or absent.Although
originally appreciated as a functional member of the inhibitor of apoptosis gene family,1 it is
now clear that survivin uniquely regulates numerous cellular networks essential for tumor …
Commentary to:
A survivin specific T-cell clone from a breast cancer patient displays universal tumor cell lysis
Rikke Bæk Sørensen, Inge Marie Svane, Per thor Straten, Mads Hald Andersen
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