Cytogenetic analyses in acute myeloid leukemia (AML) and acute lymphoblastic leukemia
(ALL) have revealed a great number of non-random chromosome abnormalities. In many
instances, molecular studies of these abnormalities identified specific genes implicated in
the process of leukemogenesis. The more common chromosome aberrations have been
associated with specific laboratory and clinical characteristics, and are now being used as
diagnostic and prognostic markers guiding the clinician in selecting the most effective …