Changes in fluid-phase endocytosis in the rat with age and their relation to total albumin elimination
GJMJ Horbach, REW van Leeuwen, SH Yap… - Mechanisms of ageing …, 1986 - Elsevier
Rates of fluid-phase endocytosis were determined in several organs and tissues of female
WAG/Rij rats of several ages by using 125 I-labelled polyvinylpyrrolidone ([125 I]-PVP) as a
marker. Liver, muscle and skin accounted for a high level of [125 I] PVP uptake 28 h after
injection. When PVP uptake was expressed per gram of organ/tissue, the liver and spleen
were found to be the most active. An age-related increase in [125 I] PVP uptake was seen at
between 12 and 36 months of age in liver, kidneys and heart. Except for the kidneys this …
WAG/Rij rats of several ages by using 125 I-labelled polyvinylpyrrolidone ([125 I]-PVP) as a
marker. Liver, muscle and skin accounted for a high level of [125 I] PVP uptake 28 h after
injection. When PVP uptake was expressed per gram of organ/tissue, the liver and spleen
were found to be the most active. An age-related increase in [125 I] PVP uptake was seen at
between 12 and 36 months of age in liver, kidneys and heart. Except for the kidneys this …
