Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
F Ishikawa, K Miyazono, U Hellman, H Drexler… - Nature, 1989 - nature.com
F Ishikawa, K Miyazono, U Hellman, H Drexler, C Wernstedt, K Hagiwara, K Usuki, F Takaku…
Nature, 1989•nature.comCloning and sequencing of the complementary DNA for platelet-derived endothelial cell
growth factor indicates that it is a novel factor distinct from previously characterized proteins.
The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial
cell growth and chemotaxis in vitro and angiogenesis in vivo.
growth factor indicates that it is a novel factor distinct from previously characterized proteins.
The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial
cell growth and chemotaxis in vitro and angiogenesis in vivo.
Abstract
Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo.
nature.com
