Serum antibody to inner ear proteins in patients with progressive hearing loss: correlation with disease activity and response to corticosteroid treatment
RA Moscicki, JE San Martin, CH Quintero, SD Rauch… - Jama, 1994 - jamanetwork.com
Objective.—To test whether detection of serum antibody to a 68-kd inner ear protein
distinguishes among different causes of sensorineural hearing loss, and identifies patients
with active disease and those likely to respond to corticosteroid therapy. Design.—Serum
samples were tested by Western blot using bovine inner ear extract as antigen, and results
were correlated with patient information obtained by chart review. Setting.—Referral center.
Subjects of Study.—Serum samples were obtained from patients with idiopathic …
distinguishes among different causes of sensorineural hearing loss, and identifies patients
with active disease and those likely to respond to corticosteroid therapy. Design.—Serum
samples were tested by Western blot using bovine inner ear extract as antigen, and results
were correlated with patient information obtained by chart review. Setting.—Referral center.
Subjects of Study.—Serum samples were obtained from patients with idiopathic …
