Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology
WE Wright, JW Shay - Nature medicine, 2000 - nature.com
WE Wright, JW Shay
Nature medicine, 2000•nature.comTelomere dynamics in cancer progression and prevention: fundamental differences in human
and mouse telomere biology | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best
experience, we recommend you use a more up to date browser (or turn off compatibility mode
in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site
without styles and JavaScript. Advertisement Nature Medicine View all journals Search My …
and mouse telomere biology | Nature Medicine Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best
experience, we recommend you use a more up to date browser (or turn off compatibility mode
in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site
without styles and JavaScript. Advertisement Nature Medicine View all journals Search My …
Abstract
Cells from the telomerase knockout mouse immortalize with an approximately ten million-fold greater frequency than human cells. In this commentary, Wright and Shay discuss the implications of this difference between mice and men and its relationship to cancer.
nature.com
