The induction of intercellular adhesion molecule 1 (ICAM-1) expression on human fetal astrocytes by interferon-λ, tumor necrosis factor α, lymphotoxin, and interleukin …
EM Frohman, TC Frohman, ML Dustin… - Journal of …, 1989 - Elsevier
Antigen presentation reactions are dependent upon the expression of the class II major
histocompatibility antigens (MHC), the T-cell receptor, and the presented antigen. Recent
studies demonstrate that such processes also require the presence of adhesion molecules
such as lymphocyte functional antigen 1 (LFA-1) and its cell surface ligand, intercellular
adhesion molecule 1 (ICAM-1). It has been suggested that the brain astrocyte can function
as a facultative antigen presenting cell (APC). This hypothesis is based upon th ability to …
histocompatibility antigens (MHC), the T-cell receptor, and the presented antigen. Recent
studies demonstrate that such processes also require the presence of adhesion molecules
such as lymphocyte functional antigen 1 (LFA-1) and its cell surface ligand, intercellular
adhesion molecule 1 (ICAM-1). It has been suggested that the brain astrocyte can function
as a facultative antigen presenting cell (APC). This hypothesis is based upon th ability to …
