Postnatal expression of VEGF and its receptor flk-1 in peripheral ganglia

M Sondell, M Kanje - Neuroreport, 2001 - journals.lww.com
Abstract The postnatal (P0–P12) and adult expression of vascular endothelial growth factor
and its receptor flk-1 was investigated in superior cervical (SCG) and dorsal root ganglia
(DRG) in mice by immunocytochemistry. At P0 all neurons in SCG and DRG contained
VEGF. The number of VEGF-immunoreactive neurons in DRG but not in SCG, decreased
postnatally and reached adult levels (34%) at P12. At P0 flk-1 was found in virtually all
neurons in the SCG and in roughly half of the neurons in DRG. The number of flk-1 positive …