Correct positioning of neurons during embryonic development of the brain depends, among
other processes, on the proper transmission of the reelin signal into the migrating cells via
the interplay of its receptors with cytoplasmic signal transducers. Cellular components of this
signaling pathway characterized to date are cell surface receptors for reelin like
apolipoprotein E receptor 2 (ApoER2), very low density lipoprotein receptor (VLDLR), and
cadherin-related neuronal receptors, and intracellular components like Disabled-1 and the …