Decorin interacts with fibrillar collagen of embryonic and adult human skin
R Fleischmajer, LW Fisher, ED MacDonald… - Journal of structural …, 1991 - Elsevier
Abstract Biglycan (PG-I, BGN) and decorin (PG-II, DCN) are small proteoglycans that have
been isolated in cartilage, skin, and bone. Although the function of biglycan is unknown,
there is biochemical evidence that decorin interacts with fibrillar collagens (type I, type II).
The purpose of this study was to perform immunofluorescence and immunoelectron
microscopy and immunoblotting of human embryonic and adult skin with antibodies directed
against biglycan and decorin. These antibodies were developed against synthetic peptides …
been isolated in cartilage, skin, and bone. Although the function of biglycan is unknown,
there is biochemical evidence that decorin interacts with fibrillar collagens (type I, type II).
The purpose of this study was to perform immunofluorescence and immunoelectron
microscopy and immunoblotting of human embryonic and adult skin with antibodies directed
against biglycan and decorin. These antibodies were developed against synthetic peptides …
