[HTML][HTML] A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF
LH Wang, RG Kalb, SM Strittmatter - Journal of Biological Chemistry, 1999 - ASBMB
M-SemF is a membrane-associated, neurally enriched member of the semaphorin family of
axon guidance signals. We considered whether the cytoplasmic domain of M-SemF might
possess a signaling function and/or might control the distribution of M-SemF on the cell
surface. We identify a PDZ-containing neural protein as an M-SemF cytoplasmic domain-
associated protein (SEMCAP-1). SEMCAP-2 is a closely related nonneuronal protein.
SEMCAP-1 has recently also been identified as GIPC, by virtue of its interaction with the …
axon guidance signals. We considered whether the cytoplasmic domain of M-SemF might
possess a signaling function and/or might control the distribution of M-SemF on the cell
surface. We identify a PDZ-containing neural protein as an M-SemF cytoplasmic domain-
associated protein (SEMCAP-1). SEMCAP-2 is a closely related nonneuronal protein.
SEMCAP-1 has recently also been identified as GIPC, by virtue of its interaction with the …
